Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Oct;17(10):821-6.
doi: 10.1016/j.annepidem.2007.04.003. Epub 2007 Jul 2.

A prospective study of green tea consumption and oral cancer incidence in Japan

Reiko Ide  1 , Yoshihisa Fujino, Yoshiharu Hoshiyama, Tetsuya Mizoue, Tatsuhiko Kubo, Truong-Minh Pham, Kiyoyumi Shirane, Noritaka Tokui, Kiyomi Sakata, Akiko Tamakoshi, Takesumi Yoshimura; JACC Study Group
Affiliations

A prospective study of green tea consumption and oral cancer incidence in Japan

Reiko Ide et al. Ann Epidemiol. 2007 Oct.

Abstract

Purpose: To examine the relation of green tea consumption with oral carcinogenesis, we prospectively analyzed data from a nationwide large-scale cohort study in Japan.

Methods: A total of 20,550 men and 29,671 women aged 40-79 years, without any history of oral and pharyngeal cancer at baseline survey, were included in the present study. During a mean follow-up period of 10.3 years, 37 oral cancer cases were identified. The Cox proportional hazard model was used to estimate the hazard ratio (HR) and 95% confidence interval (95% CI) for oral cancer according to green tea consumption by sex, while adjusting for age, smoking, alcohol drinking, and other dietary factors.

Results: For women, the HRs of oral cancer for green tea consumption of 1-2, 3-4, and 5 or more cups per day were 0.51 (95% CI: 0.10-2.68), 0.60 (95% CI: 0.17-2.10), and 0.31 (95% CI: 0.09-1.07), respectively, compared with those who drank less than one cup per day (p for trend, 0.08). For men, no such trends were observed.

Conclusions: Our findings did not suggest a prominent inverse association of green tea consumption with oral cancer, although there was a tendency for a reduced risk in women.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

Publication types

LinkOut - more resources