doi: 10.1073/pnas.73.1.73.
A ribosome-dependent GTPase from yeast distinct from elongation factor 2
- PMID: 174100
- PMCID: PMC335841
- DOI: 10.1073/pnas.73.1.73
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A ribosome-dependent GTPase from yeast distinct from elongation factor 2
Proc Natl Acad Sci U S A.
1976 Jan.
Abstract
Three proteins required for poly(U)-directed polyphenylalanine synthesis have been separated from yeast. Two of the factors correspond to the elongation factors 1 and 2 described for other eukaryotic systems, according to the criteria of phenylalanyl-tRNA binding and diphtheria toxin-catalyzed ADP-ribosylation. The third protein, while absolutely required for polyphenylalanine synthesis, was a more active ribosome-dependent GTPase than elongation factor 2.
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