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Comment
. 2007 Mar;71(6):477-9.
doi: 10.1038/sj.ki.5002150.

Renal response to repeated exposure to endotoxin: implications for acute kidney injury

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Comment

Renal response to repeated exposure to endotoxin: implications for acute kidney injury

K A Nath. Kidney Int. 2007 Mar.
Free article

Abstract

Zager and colleagues demonstrate that endotoxin tolerance is accompanied by an augmented inflammatory response in the kidney, the latter also exhibiting cholesterol-dependent cytoresistance. These novel findings are discussed mainly from the perspective of acute kidney injury and its prevention by preconditioning and the elicitation of cytoprotective pathways.

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