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. 2006 Nov;12(11):1744-7.
doi: 10.3201/eid1211.060542.

Fatal avian influenza A H5N1 in a dog

Thaweesak Songserm  1 , Alongkorn Amonsin, Rungroj Jam-on, Namdee Sae-Heng, Nuananong Pariyothorn, Sunchai Payungporn, Apiradee Theamboonlers, Salin Chutinimitkul, Roongroje Thanawongnuwech, Yong Poovorawan
Affiliations

Fatal avian influenza A H5N1 in a dog

Thaweesak Songserm et al. Emerg Infect Dis. 2006 Nov.

Abstract

Avian influenza H5N1 virus is known to cross the species barrier and infect humans and felines. We report a fatal H5N1 infection in a dog following ingestion of an H5N1-infected duck during an outbreak in Thailand in 2004. With new reports of H5N1 virus continuing across Asia, Europe, and Africa, this finding highlights the need for monitoring of domestic animals during outbreaks.

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Figures

Figure 1
Figure 1
Gross and microscopic lesions from dog infected with highly pathogenic avian influenza (HPAI) H5N1. A) Severe congestion and edema in the lung. B) Lung histopathologic results showing severe pulmonary edema and hemorrhage with black-brown particles (hemosiderin) (magnification ×100). C) Liver histopathologic changes showing necrotic foci (pale area) (magnification ×100). D) Immunohistochemical results: the nucleoprotein of the virus is detected in nuclei of hepatocytes with brown granule (magnification ×200).
Figure 2
Figure 2
Phylogenetic analysis of the hemagglutinin (A) and neuraminidase (B) gene sequences of the H5N1 influenza virus isolated from a dog's lung (KU-08), compared with other HA and NA sequences stored in GenBank.
See this image and copyright information in PMC

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References

    1. Chotpitayasunondh T, Ungchusak K, Hanshaoworakul W, Chunsuthiwat S, Sawanpanyalert P, Kijphati R, et al. Human disease from influenza A (H5N1), Thailand, 2004. Emerg Infect Dis. 2005;11:201–9. - PMC - PubMed
    1. Songserm T, Amonsin A, Jam-on R, Sae-Heng N, Meemak N, Pariyothorn N, et al. Avian influenza H5N1 in naturally infected domestic cat. Emerg Infect Dis. 2006;12:681–3. - PMC - PubMed
    1. Keawcharoen J, Oraveerakul K, Kuiken T, Fouchier RA, Amonsin A, Payungporn S, et al. Avian influenza H5N1 in tigers and leopards. Emerg Infect Dis. 2004;10:2189–91. - PMC - PubMed
    1. Thanawongnuwech R, Amonsin A, Tantilertcharoen R, Damrongwatanapokin S, Theamboonlers A, Payungporn S, et al. Probable tiger-to-tiger transmission of avian influenza H5N1. Emerg Infect Dis. 2005;11:699–701. - PMC - PubMed
    1. Amonsin A, Payungporn S, Theamboonlers A, Thanawongnuwech R, Suradhat S, Pariyothorn N, et al. Genetic characterization of H5N1 influenza A viruses isolated from zoo tigers in Thailand. Virology. 2006;344:480–91. 10.1016/j.virol.2005.08.032 - DOI - PubMed

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