Review
doi: 10.1016/0167-5699(91)90010-Q.
Complement evasion strategies of microorganisms
Affiliations
- PMID: 1721820
- DOI: 10.1016/0167-5699(91)90010-Q
Item in Clipboard
Review
Complement evasion strategies of microorganisms
Immunol Today.
1991 Sep.
Abstract
The success of microorganisms as human pathogens stems partly from their ability to evade recognition and/or avoid destruction by complement and other natural and acquired defense mechanisms. Here, Neil Cooper reviews the various mechanisms that pathogens have evolved to evade the destructive actions of the complement system, with particular emphasis on the many remarkable examples of the duplication of complement-like structural and functional epitopes by microorganisms. Such mimicry not only enables the pathogens to avoid destruction by complement-mediated mechanisms but also, in a number of instances, facilitates infection.
Similar articles
-
The membrane attack pathway of complement.Year Immunol. 1989-1990;6:229-44. Year Immunol. 1989. PMID: 2701906 Review. No abstract available.
-
Complement evasion of pathogens: common strategies are shared by diverse organisms.Mol Immunol. 2007 Sep;44(16):3850-7. doi: 10.1016/j.molimm.2007.06.149. Mol Immunol. 2007. PMID: 17768102 Review.
-
[The role of complement system in infections].Tidsskr Nor Laegeforen. 1991 Jan 10;111(1):53-8. Tidsskr Nor Laegeforen. 1991. PMID: 2000589 Review. Norwegian.
-
Parasite interaction with host complement: beyond attack regulation.Trends Parasitol. 2004 Sep;20(9):407-12. doi: 10.1016/j.pt.2004.07.001. Trends Parasitol. 2004. PMID: 15324730 Review.
-
Big MAC attack: complement proteins cause leaky patches.Immunol Today. 1991 Sep;12(9):316-8; discussion 321. doi: 10.1016/0167-5699(91)90006-F. Immunol Today. 1991. PMID: 1721818 Review. No abstract available.
Cited by
-
Regulation of interleukin-12 by complement receptor 3 signaling.J Exp Med. 1997 Jun 2;185(11):1987-95. doi: 10.1084/jem.185.11.1987. J Exp Med. 1997. PMID: 9166428 Free PMC article.
-
Facilitation of complement-dependent killing of the Lyme disease spirochete, Borrelia burgdorferi, by specific immunoglobulin G Fab antibody fragments.Infect Immun. 1993 Jun;61(6):2532-6. doi: 10.1128/iai.61.6.2532-2536.1993. Infect Immun. 1993. PMID: 8500889 Free PMC article.
-
Blocking measles virus infection with a recombinant soluble form of, or monoclonal antibodies against, membrane cofactor protein of complement (CD46).Immunology. 1995 Apr;84(4):619-25. Immunology. 1995. PMID: 7790036 Free PMC article.
-
Humoral response to herpes simplex virus is complement-dependent.Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12708-12. doi: 10.1073/pnas.96.22.12708. Proc Natl Acad Sci U S A. 1999. PMID: 10535987 Free PMC article.
-
Neutralizing antiviral antibody responses.Adv Immunol. 2001;79:1-53. doi: 10.1016/s0065-2776(01)79001-3. Adv Immunol. 2001. PMID: 11680006 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
