Regulation of TRP channels by PIP(2)
- PMID: 17031667
- DOI: 10.1007/s00424-006-0153-7
Regulation of TRP channels by PIP(2)
Abstract
Transient receptor potential (TRP) channels are regulated by a wide variety of physical and chemical factors. Recently, several members of the TRP channel family were reported to be regulated by phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P(2), PIP(2)). This review will summarize the current knowledge on PIP(2) regulation of TRP channels and discuss the possibility that PIP(2) is a common regulator of mammalian TRP channels.
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