Review
doi: 10.1146/annurev.genet.40.110405.090636.
DNA helicases required for homologous recombination and repair of damaged replication forks
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- PMID: 16856806
- DOI: 10.1146/annurev.genet.40.110405.090636
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Review
DNA helicases required for homologous recombination and repair of damaged replication forks
Annu Rev Genet.
2006.
Abstract
DNA helicases are found in all kingdoms of life and function in all DNA metabolic processes where the two strands of duplex DNA require to be separated. Here, we review recent developments in our understanding of the roles that helicases play in the intimately linked processes of replication fork repair and homologous recombination, and highlight how the cell has evolved many distinct, and sometimes antagonistic, uses for these enzymes.
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