Review
doi: 10.1016/j.cell.2006.05.015.
A phosphatase controls the fate of receptor-regulated Smads
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- PMID: 16751094
- DOI: 10.1016/j.cell.2006.05.015
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Review
A phosphatase controls the fate of receptor-regulated Smads
Cell.
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Free article
Abstract
In this issue of Cell, Lin et al. (2006) answer one of the long-standing questions in the TGFbeta field by identifying a phosphatase, PPM1A, that directly dephosphorylates Smad2 and Smad3 to limit their activation.
Comment on
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PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling.Cell. 2006 Jun 2;125(5):915-28. doi: 10.1016/j.cell.2006.03.044. Cell. 2006. PMID: 16751101 Free PMC article.
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