Review
doi: 10.1016/j.molcel.2006.05.002.
If the prophet does not come to the mountain: dynamics of signaling complexes in NF-kappaB activation
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- PMID: 16713572
- DOI: 10.1016/j.molcel.2006.05.002
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Review
If the prophet does not come to the mountain: dynamics of signaling complexes in NF-kappaB activation
Mol Cell.
.
Free article
Abstract
Recruitment of the NF-kappaB-activating IKK signaling complex to the TNF receptor is shown to be driven by induced binding of NEMO, a regulatory component of this complex, to K63-linked polyubiquitin chains attached to RIP1, a receptor-associated adaptor protein (Ea et al., 2006 [in a recent issue of Molecular Cell]; Li et al., 2006; Wu et al., 2006a).
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