Association of inflammatory markers with socioeconomic status
- PMID: 16567379
- DOI: 10.1093/gerona/61.3.284
Association of inflammatory markers with socioeconomic status
Abstract
Background: This study examines the association between socioeconomic status (SES) and inflammatory markers in well-functioning older adults and seeks to determine whether any association remains after adjusting for biomedical and behavioral factors typically related to elevated serum levels of inflammatory markers.
Methods: Data were obtained from 3044 men and women, aged 70-79 from Pittsburgh, Pennsylvania and Memphis, Tennessee participating in the Health, Aging and Body Composition study. Three indicators of SES were used: education, income, and ownership of financial assets. Serum levels of interleukin-6, C-reactive protein, and tumor necrosis factor-alpha were measured.
Results: Low SES was associated with significantly elevated levels of interleukin-6, C-reactive protein, and tumor necrosis factor-alpha compared to high SES. Behavioral factors (including smoking, drinking, obesity) explained a substantial part of the inverse association between SES and inflammatory markers. Adjustment for prevalent diseases (including heart diseases, lung disease, and diabetes) associated with inflammation explained less of the association.
Conclusions: This study suggests that interventions to improve health behaviors, even in old age and especially in low SES groups, may be useful in reducing risks associated with inflammation.
Comment in
-
Association of inflammatory markers with socioeconomic status: more could be explored with multiple regression analysis.J Gerontol A Biol Sci Med Sci. 2007 Mar;62(3):336. doi: 10.1093/gerona/62.3.336. J Gerontol A Biol Sci Med Sci. 2007. PMID: 17389733 No abstract available.
Similar articles
-
Association between sleep duration and mortality is mediated by markers of inflammation and health in older adults: the Health, Aging and Body Composition Study.Sleep. 2015 Feb 1;38(2):189-95. doi: 10.5665/sleep.4394. Sleep. 2015. PMID: 25348127 Free PMC article.
-
Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study.J Am Geriatr Soc. 2004 Jul;52(7):1098-104. doi: 10.1111/j.1532-5415.2004.52307.x. J Am Geriatr Soc. 2004. PMID: 15209647
-
Community socioeconomic status is associated with circulating interleukin-6 and C-reactive protein.Psychosom Med. 2008 Jul;70(6):646-52. doi: 10.1097/PSY.0b013e31817b8ee4. Psychosom Med. 2008. PMID: 18606725
-
Association of socioeconomic status with inflammatory markers: a two cohort comparison.Prev Med. 2015 Feb;71:12-9. doi: 10.1016/j.ypmed.2014.11.031. Epub 2014 Dec 5. Prev Med. 2015. PMID: 25482420
-
Is there a biomedical explanation for socioeconomic differences in incident mobility limitation?J Gerontol A Biol Sci Med Sci. 2005 Aug;60(8):1022-7. doi: 10.1093/gerona/60.8.1022. J Gerontol A Biol Sci Med Sci. 2005. PMID: 16127107
Cited by
-
Individual and neighborhood socioeconomic status and inflammation in Mexican American women: what is the role of obesity?Psychosom Med. 2012 Jun;74(5):535-42. doi: 10.1097/PSY.0b013e31824f5f6d. Epub 2012 May 11. Psychosom Med. 2012. PMID: 22582313 Free PMC article. Clinical Trial.
-
Socioeconomic Status and Biological Risks for Health and Illness Across the Life Course.J Gerontol B Psychol Sci Soc Sci. 2020 Feb 14;75(3):613-624. doi: 10.1093/geronb/gby108. J Gerontol B Psychol Sci Soc Sci. 2020. PMID: 30252104 Free PMC article.
-
Socioeconomic and psychosocial predictors of interleukin-6 in the MIDUS national sample.Health Psychol. 2010 Nov;29(6):626-35. doi: 10.1037/a0021360. Health Psychol. 2010. PMID: 20954777 Free PMC article.
-
Association Between Socioeconomic Status Mobility and Inflammation Markers Among White and Black Adults in the United States: A Latent Class Analysis.Psychosom Med. 2020 Feb/Mar;82(2):224-233. doi: 10.1097/PSY.0000000000000752. Psychosom Med. 2020. PMID: 31592888 Free PMC article.
-
Frontiers in the use of biomarkers of health in research on stress and aging.J Gerontol B Psychol Sci Soc Sci. 2010 Sep;65(5):513-25. doi: 10.1093/geronb/gbq049. Epub 2010 Jul 20. J Gerontol B Psychol Sci Soc Sci. 2010. PMID: 20647348 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Research Materials