Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Feb;84(1):110-5.
doi: 10.1111/j.1600-0420.2005.00551.x.

Monoamine receptors in human corneal epithelium and endothelium

Affiliations
Free article

Monoamine receptors in human corneal epithelium and endothelium

Matthias Grueb et al. Acta Ophthalmol Scand. 2006 Feb.
Free article

Abstract

Purpose: Monoamine receptors are found throughout the body. Reports about the presence of monoamine receptors in the human cornea are inconsistent.

Methods: Immunohistochemistry, immunofluorescence and immunoblotting were used to localize monoamine receptor sites on human corneal epithelium and endothelium.

Results: Antibodies to alpha-1, beta-1 and beta-2 adrenergic receptors and to D1-like and 5HT-7 receptors were bound in corneal epithelium. Antibodies to alpha-1, alpha-2A, beta-1 and beta-2 adrenergic receptors and to 5HT-7 receptors were bound in corneal endothelium.

Conclusions: Our data demonstrate the presence of several monoamine receptors in the human cornea. These receptors may play a role in the regulation of fluid transport or corneal homeostasis.

PubMed Disclaimer

Similar articles

Cited by

LinkOut - more resources