doi: 10.1007/s00203-005-0057-5.
Epub 2006 Jan 10.
The DD-carboxypeptidase activity encoded by pbp4B is not essential for the cell growth of Escherichia coli
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- PMID: 16402224
- DOI: 10.1007/s00203-005-0057-5
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The DD-carboxypeptidase activity encoded by pbp4B is not essential for the cell growth of Escherichia coli
Arch Microbiol.
2006 Mar.
Abstract
The gene (pbp4B) encoding a putative DD-carboxypeptidase has been deleted in Escherichia coli and it is shown to be not essential for cell division. Disruption of the gene in a genetic background where all putative activities of DD-carboxypeptidases and/or DD-endopeptidases had been eliminated indicates that these activities are not required for cell growth in enterobacteria. The penicillin-binding capacity and a low DD-carboxypeptidase activity of PBP4B are demonstrated.
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