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. 2005 Dec 1;438(7068):578-80.
doi: 10.1038/nature04394.

Membranes are more mosaic than fluid

Donald M Engelman  1
Affiliations

Membranes are more mosaic than fluid

Donald M Engelman. Nature. .

Abstract

The wealth of new data on membrane protein structures and functions is changing our general view of membrane architecture. Some of the key themes that are emerging are that membranes are patchy, with segregated regions of structure and function, that lipid regions vary in thickness and composition, and that crowding and ectodomains limit exposure of lipid to the adjacent aqueous regions.

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