Review
doi: 10.1016/j.febslet.2005.08.069.
Epub 2005 Sep 20.
RNA silencing in Drosophila
Affiliations
- PMID: 16198344
- DOI: 10.1016/j.febslet.2005.08.069
Item in Clipboard
Review
RNA silencing in Drosophila
FEBS Lett.
.
Free article
Abstract
Knowledge of the role of RNA in affecting gene expression has expanded in the past several years. Small RNAs serve as homology guides to target messenger RNAs for destruction at the post-transcriptional level in the experimental technique known as RNA interference and in the silencing of some transgenes. These small RNAs are also involved in sequence-specific targeting of chromatin modifications for transcriptional silencing of transgenes, transposable elements, heterochromatin and some cases of Polycomb-mediated gene silencing. RNA silencing processes in Drosophila are described.
Similar articles
-
Global analysis of siRNA-mediated transcriptional gene silencing.Bioessays. 2005 Dec;27(12):1209-12. doi: 10.1002/bies.20328. Bioessays. 2005. PMID: 16299769
-
Dynamic and reversibility of heterochromatic gene silencing in human disease.Cell Res. 2005 Sep;15(9):679-90. doi: 10.1038/sj.cr.7290337. Cell Res. 2005. PMID: 16212874 Review.
-
Those interfering little RNAs! Silencing and eliminating chromatin.Curr Opin Genet Dev. 2004 Apr;14(2):174-80. doi: 10.1016/j.gde.2004.02.006. Curr Opin Genet Dev. 2004. PMID: 15196464 Review.
-
RNA-directed transcriptional gene silencing in mammals.Trends Genet. 2005 Jul;21(7):370-3. doi: 10.1016/j.tig.2005.05.007. Trends Genet. 2005. PMID: 15908035 Review.
-
An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster.Nature. 2007 Nov 8;450(7167):304-8. doi: 10.1038/nature06263. Epub 2007 Oct 21. Nature. 2007. PMID: 17952056
Cited by
-
E(var)3-9 of Drosophila melanogaster encodes a zinc finger protein.Genetics. 2007 Sep;177(1):167-78. doi: 10.1534/genetics.107.076521. Epub 2007 Jul 29. Genetics. 2007. PMID: 17660546 Free PMC article.
-
Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline.Nucleic Acids Res. 2007;35(16):5430-8. doi: 10.1093/nar/gkm576. Epub 2007 Aug 15. Nucleic Acids Res. 2007. PMID: 17702759 Free PMC article.
-
Epigenetic Factors of Disease.Diseases. 2019 Jun 14;7(2):42. doi: 10.3390/diseases7020042. Diseases. 2019. PMID: 31197091 Free PMC article.
-
Antiviral silencing in animals.FEBS Lett. 2005 Oct 31;579(26):5965-73. doi: 10.1016/j.febslet.2005.08.034. Epub 2005 Aug 31. FEBS Lett. 2005. PMID: 16154568 Free PMC article. Review.
-
Target validation to biomarker development: focus on RNA interference.Mol Diagn Ther. 2008;12(2):63-70. doi: 10.1007/BF03256271. Mol Diagn Ther. 2008. PMID: 18422370 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
Miscellaneous
