Review
doi: 10.1039/b418841c.
Epub 2005 Apr 4.
Cucurbitacins and cucurbitane glycosides: structures and biological activities
Affiliations
- PMID: 16010347
- DOI: 10.1039/b418841c
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Review
Cucurbitacins and cucurbitane glycosides: structures and biological activities
Nat Prod Rep.
2005 Jun.
Erratum in
- Nat Prod Rep. 2005 Dec;22(6):794-5
Abstract
The natural cucurbitacins constitute a group of triterpenoid substances which are well-known for their bitterness and toxicity. Structurally, they are characterized by the tetracyclic cucurbitane nucleus skeleton, namely, 19-(10-->9beta)-abeo-10alpha-lanost-5-ene (also known as 9beta-methyl-19-norlanosta-5-ene), with a variety of oxygen substitutions at different positions. According to the characteristics of their structures, cucurbitacins are divided into twelve categories. The biological effects of the cucurbitacins are also covered.
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