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. 1992 Feb;26(2):133-46.
doi: 10.1002/jbm.820260202.

Biological response to chopped-carbon-fiber-reinforced peek

K A Jockisch  1 , S A Brown, T W Bauer, K Merritt
Affiliations

Biological response to chopped-carbon-fiber-reinforced peek

K A Jockisch et al. J Biomed Mater Res. 1992 Feb.

Abstract

Polymer composites are being recognized as important implant materials for fracture fixation plates. The use of a composite material is dependent upon the mechanical properties of the material and its biocompatibility. The primary objective of this project was to evaluate 30% chopped-carbon-fiber-reinforced poly(etheretherketone) (CFRPEEK) as a potential material for use as a fracture fixation plate. A two-phase study was conducted. The first phase analyzed the short-term biocompatibility of CFRPEEK through rabbit muscle implant testing. CFRPEEK exhibited a nonspecific foreign body tissue reaction similar to the response observed with ultra-high-molecular-weight polyethylene (UHMWPE). In the second phase, four-hole CFRPEEK plates were implanted as internal fixation devices for transverse midshaft femoral osteotomies in beagles. The plates were effective in promoting fracture healing. A nonspecific foreign body reaction was observed to the plates and to particulate debris.

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