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. 2005 Jan 3;15(1):81-4.
doi: 10.1016/j.bmcl.2004.10.029.

Optimization of pyrrolidinone based HIV protease inhibitors

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Optimization of pyrrolidinone based HIV protease inhibitors

Ronald G Sherrill et al. Bioorg Med Chem Lett. .

Abstract

Optimization of P1-substituted pyrrolidinone based HIV protease inhibitors has yielded analogs with very potent antiviral activity.

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