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. 2004 Aug;48(8):3200-2.
doi: 10.1128/AAC.48.8.3200-3202.2004.

Susceptibility of Chlamydia trachomatis to excipients commonly used in topical microbicide formulations

M F Lampe  1 , L C Rohan, M C Skinner, W E Stamm
Affiliations

Susceptibility of Chlamydia trachomatis to excipients commonly used in topical microbicide formulations

M F Lampe et al. Antimicrob Agents Chemother. 2004 Aug.

Abstract

Commonly used "inactive" pharmaceutical excipients were tested in a previously developed minimum cidal concentration assay to assess their ability to kill Chlamydia trachomatis topically. Sixteen excipients were evaluated in these studies under various conditions. A range of activities was found among the excipients that could be tested in our assay system.

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References

    1. Ballweber, L. M., J. E. Jaynes, W. E. Stamm, and M. F. Lampe. 2002. In vitro microbicidal activity of cecropin peptides D2A21 and D4E1 and gel formulations containing 0.1 to 2% D2A21 against Chlamydia trachomatis. Antimicrob. Agents Chemother. 46:34-41. - PMC - PubMed
    1. Belec, L., C. Tevi-Benissan, A. Bianchi, S. Citigny, M. Beumont-Mauviel, A. Si-Mohamed, and J. E. Malkin. 2000. In vitro inactivation of Chlamydia trachomatis and a panel of DNA (HSV-2, CMV, adenovirus, BK virus) and RNA (RSV, enterovirus) viruses by the spermicide benzalkonium chloride. J. Antimicrob. Chemother. 46:685-693. - PubMed
    1. Chong-Cerrillo, C., M. E. Selsted, E. M. Peterson, and L. M. de la Maza. 2003. Susceptibility of human and murine Chlamydia trachomatis serovars to granulocyte- and epithelium-derived antimicrobial peptides. J. Peptide Res. 61:237-242. - PubMed
    1. Garg, S., K. R. Tambwekar, K. Vermani, A. Garg, C. L. Kaul, and L. J. D. Zaneveld. 2001. Compendium of pharmaceutical excipients for vaginal formulations. Pharm. Technol. 25:14-24. [Online.]
    1. Herold, B. C., R. Kirkpatrick, D. Marcellino, A. Travelstead, V. Pilipenko, H. Krasa, J. Bremer, L. J. Dong, and M. D. Cooper. 1999. Bile salts: natural detergents for the prevention of sexually transmitted diseases. Antimicrob. Agents Chemother. 43:745-751. - PMC - PubMed

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