Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2004 Aug;78(15):7863-6.
doi: 10.1128/JVI.78.15.7863-7866.2004.

Severe acute respiratory syndrome coronavirus phylogeny: toward consensus

Affiliations

Severe acute respiratory syndrome coronavirus phylogeny: toward consensus

Alexander E Gorbalenya et al. J Virol. 2004 Aug.
No abstract available

PubMed Disclaimer

Figures

FIG. 1.
FIG. 1.
Overview of the SARS-CoV genome organization and proteins (20). The positions of coronavirus group-specific genetic and structural markers are indicated. SARS-CoV has the markers of group 2 coronaviruses. In the N-terminal part of the S protein, only Cys residues are distributed in a group-specific fashion (5) (dashed line). SUD, SARS-CoV-unique domain; PL2pro, group 2 papain-like protease 2; TM2, transmembrane domain 2; 3CLpro, chymotrypsin-like protease related to 3Cpro of picornaviruses.
FIG. 2.
FIG. 2.
Two alternative scenarios of SARS-CoV evolution, shown on the same coronavirus tree with alternative roots. The SARS-CoV branch splits, for the sake of comparison, from an ancestor of the other known coronaviruses (A) or, as defined in reference , from the group 2 branch (B). IBV, infectious bronchitis virus; TGEV, porcine transmissible gastroenteritis virus; EToV, equine torovirus. BCoV-Lun and other BCoV strains are most closely related to HCoV OC43, which was not included in the analysis.

Similar articles

Cited by

References

    1. Bell, Y. C., B. L. Semler, and E. Ehrenfeld. 1999. Requirements for RNA replication of a poliovirus replicon by coxsackievirus B3 RNA polymerase. J. Virol. 73:9413-9421. - PMC - PubMed
    1. Bujarski, J. J. 1997. Experimental systems of genetic recombination and defective RNA formation in RNA viruses. Part II. Semin. Virol. 8:75-76.
    1. Chouljenko, V. N., X. Q. Lin, J. Storz, K. G. Kousoulas, and A. E. Gorbalenya. 2001. Comparison of genomic and predicted amino acid sequences of respiratory and enteric bovine coronaviruses isolated from the same animal with fatal shipping pneumonia. J. Gen. Virol. 82:2927-2933. - PubMed
    1. de Haan, C. A. M., P. S. Masters, X. L. Shen, S. Weiss, and P. J. M. Rottier. 2002. The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host. Virology 296:177-189. - PMC - PubMed
    1. Eickmann, M., S. Becker, H. D. Klenk, H. W. Doerr, K. Stadler, S. Censini, S. Guidotti, V. Masignani, M. Scarselli, M. Mora, C. Donati, J. H. Han, H. C. Song, S. Abrignani, A. Covacci, and R. Rappuoli. 2003. Phylogeny of the SARS coronavirus. Science 302:1504-1505. - PubMed

MeSH terms

Substances

LinkOut - more resources