Review
doi: 10.1146/annurev.nutr.24.012003.132241.
Identification of trace element-containing proteins in genomic databases
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- PMID: 15189132
- DOI: 10.1146/annurev.nutr.24.012003.132241
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Review
Identification of trace element-containing proteins in genomic databases
Annu Rev Nutr.
2004.
Free article
Abstract
Development of bioinformatics tools provided researchers with the ability to identify full sets of trace element-containing proteins in organisms for which complete genomic sequences are available. Recently, independent bioinformatics methods were used to identify all, or almost all, genes encoding selenocysteine-containing proteins in human, mouse, and Drosophila genomes, characterizing entire selenoproteomes in these organisms. It also should be possible to search for entire sets of other trace element-associated proteins, such as metal-containing proteins, although methods for their identification are still in development.
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