Ginkgo biloba promotes short-term retention of spatial memory in rats
- PMID: 15006464
- DOI: 10.1016/j.pbb.2003.12.006
Ginkgo biloba promotes short-term retention of spatial memory in rats
Abstract
This study examines possible interactions between exposure to Ginkgo biloba extract and enriched environments on the acquisition and retention of spatial learning following massed and spaced trials. After 4 weeks of exposure to either ginkgo or vehicle, 8-week-old rats were tested using a Morris Water Maze in either massed or spaced trials. While ginkgo did not have an effect on maze acquisition or long-term retention, it did promote short-term retention of spatial memory. Following reversal training, ginkgo promoted short-term retention for two groups but impaired retention for a third. These results suggest that ginkgo has powerful effects on short-term retention that vary with training conditions.
Similar articles
-
Effects of Ginkgo biloba administered after spatial learning on water maze and radial arm maze performance in young adult rats.Pharmacol Biochem Behav. 2006 May;84(1):17-25. doi: 10.1016/j.pbb.2006.04.003. Epub 2006 Jun 5. Pharmacol Biochem Behav. 2006. PMID: 16740301
-
Effects of morphine dependence on the performance of rats in reference and working versions of the water maze.Physiol Behav. 2008 Feb 27;93(3):622-7. doi: 10.1016/j.physbeh.2007.11.002. Epub 2007 Nov 9. Physiol Behav. 2008. PMID: 18067930
-
Testosterone modulates performance on a spatial working memory task in male rats.Horm Behav. 2006 Jun;50(1):18-26. doi: 10.1016/j.yhbeh.2005.09.008. Epub 2005 Nov 2. Horm Behav. 2006. PMID: 16263125
-
NMDA receptors are involved in Ginkgo extract-induced facilitation on memory retention of passive avoidance learning in rats.Neurosci Lett. 2008 Feb 27;432(3):206-11. doi: 10.1016/j.neulet.2007.12.022. Epub 2007 Dec 23. Neurosci Lett. 2008. PMID: 18191327
-
Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and spatial reversal.Neuroscience. 2009 Mar 3;159(1):59-68. doi: 10.1016/j.neuroscience.2008.11.054. Epub 2008 Dec 16. Neuroscience. 2009. PMID: 19138728
Cited by
-
Blueberry supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young rats.Psychopharmacology (Berl). 2012 Oct;223(3):319-30. doi: 10.1007/s00213-012-2719-8. Epub 2012 May 9. Psychopharmacology (Berl). 2012. PMID: 22569815
-
Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases.Antioxid Redox Signal. 2013 May 10;18(14):1818-92. doi: 10.1089/ars.2012.4581. Epub 2012 Aug 27. Antioxid Redox Signal. 2013. PMID: 22794138 Free PMC article. Review.
-
The neuroprotective potential of flavonoids: a multiplicity of effects.Genes Nutr. 2008 Dec;3(3-4):115-26. doi: 10.1007/s12263-008-0091-4. Genes Nutr. 2008. PMID: 18937002 Free PMC article.
-
The impact of flavonoids on spatial memory in rodents: from behaviour to underlying hippocampal mechanisms.Genes Nutr. 2009 Dec;4(4):251-70. doi: 10.1007/s12263-009-0137-2. Epub 2009 Sep 2. Genes Nutr. 2009. PMID: 19727888 Free PMC article.
-
Effects of a Flavonoid-Rich Fraction on the Acquisition and Extinction of Fear Memory: Pharmacological and Molecular Approaches.Front Behav Neurosci. 2016 Jan 5;9:345. doi: 10.3389/fnbeh.2015.00345. eCollection 2015. Front Behav Neurosci. 2016. PMID: 26778988 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources