Sulindac-derived Ras pathway inhibitors target the Ras-Raf interaction and downstream effectors in the Ras pathway
- PMID: 14735533
- DOI: 10.1002/anie.200353089
Sulindac-derived Ras pathway inhibitors target the Ras-Raf interaction and downstream effectors in the Ras pathway
Similar articles
-
Identification of potent Ras signaling inhibitors by pathway-selective phenotype-based screening.Angew Chem Int Ed Engl. 2004 Jan 16;43(4):450-4. doi: 10.1002/anie.200352587. Angew Chem Int Ed Engl. 2004. PMID: 14735532 No abstract available.
-
The new sulindac derivative IND 12 reverses Ras-induced cell transformation.Cancer Res. 2002 Mar 15;62(6):1718-23. Cancer Res. 2002. PMID: 11912145
-
Protein kinase Cepsilon is oncogenic in colon epithelial cells by interaction with the ras signal transduction pathway.Oncogene. 1998 Jun 25;16(25):3345-8. doi: 10.1038/sj.onc.1201871. Oncogene. 1998. PMID: 9681835
-
Regulation of the Ras-MAPK pathway at the level of Ras and Raf.Genet Eng (N Y). 2002;24:49-66. doi: 10.1007/978-1-4615-0721-5_3. Genet Eng (N Y). 2002. PMID: 12416300 Review. No abstract available.
-
Targeting RAS signalling pathways in cancer therapy.Nat Rev Cancer. 2003 Jan;3(1):11-22. doi: 10.1038/nrc969. Nat Rev Cancer. 2003. PMID: 12509763 Review.
Cited by
-
Small molecule inhibitors of RAS proteins with oncogenic mutations.Cancer Metastasis Rev. 2020 Dec;39(4):1107-1126. doi: 10.1007/s10555-020-09911-9. Cancer Metastasis Rev. 2020. PMID: 32770300 Free PMC article. Review.
-
The RAS-Effector Interaction as a Drug Target.Cancer Res. 2017 Jan 15;77(2):221-226. doi: 10.1158/0008-5472.CAN-16-0938. Epub 2017 Jan 6. Cancer Res. 2017. PMID: 28062402 Free PMC article. Review.
-
Therapeutic Approaches to RAS Mutation.Cancer J. 2016 May-Jun;22(3):165-74. doi: 10.1097/PPO.0000000000000187. Cancer J. 2016. PMID: 27341593 Free PMC article. Review.
-
Arresting kinase suppressor of Ras in an inactive state.Chin J Cancer. 2017 Jan 9;36(1):5. doi: 10.1186/s40880-017-0181-z. Chin J Cancer. 2017. PMID: 28069069 Free PMC article.
-
8-Hydroxyquinoline-based inhibitors of the Rce1 protease disrupt Ras membrane localization in human cells.Bioorg Med Chem. 2016 Jan 15;24(2):160-78. doi: 10.1016/j.bmc.2015.11.043. Epub 2015 Nov 30. Bioorg Med Chem. 2016. PMID: 26706114 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials
Miscellaneous