doi: 10.1021/ja0386905.
Semiconductor quantum dots for photodynamic therapy
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- PMID: 14677951
- DOI: 10.1021/ja0386905
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Semiconductor quantum dots for photodynamic therapy
J Am Chem Soc.
.
Abstract
The applicability of semiconductor QDs in photodynamic therapy (PDT) was evaluated by studying the interaction between CdSe QDs with a known silicon phthalocyanine PDT photosensitizer, Pc4. The study revealed that the QDs could be used to sensitize the PDT agent through a fluorescence resonance energy transfer (FRET) mechanism, or interact directly with molecular oxygen via a triplet energy-transfer process (TET). Both mechanisms result in the generation of reactive singlet oxygen species that can be used for PDT cancer therapy.
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