Review
doi: 10.1016/s0955-0674(03)00107-8.
Synaptic adhesion molecules
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- PMID: 14519398
- DOI: 10.1016/s0955-0674(03)00107-8
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Review
Synaptic adhesion molecules
Curr Opin Cell Biol.
2003 Oct.
Abstract
Formation, differentiation and plasticity of synapses, the specialized cell-cell contacts through which neurons communicate, all require interactions between pre- and post-synaptic partners. Several synaptically localized adhesion molecules potentially capable of mediating these interactions have been identified recently. Functional studies suggest roles for some of them in target recognition (e.g. SYG-1 and sidekicks), formation and alignment of synaptic specializations (e.g. SynCAM, neuroligin and neurexin), and regulation of synaptic structure and function (e.g. cadherins and syndecan).
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