Review
doi: 10.1016/s0092-8674(02)01081-4.
Epigenetic consequences of nucleosome dynamics
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- PMID: 12419239
- DOI: 10.1016/s0092-8674(02)01081-4
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Review
Epigenetic consequences of nucleosome dynamics
Cell.
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Free article
Abstract
Current models for epigenetic gene silencing envision a static relationship between histone modifications and transcription. However, evidence for nucleosome mobility and replacement favors a dynamic model that may explain phenomena ranging from variegation to the neural restriction of Rett syndrome.
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