Blu-Ice and the Distributed Control System: software for data acquisition and instrument control at macromolecular crystallography beamlines
- PMID: 12409628
- DOI: 10.1107/s0909049502015170
Blu-Ice and the Distributed Control System: software for data acquisition and instrument control at macromolecular crystallography beamlines
Abstract
The Blu-Ice and Distributed Control System (DCS) software packages were developed to provide unified control over the disparate hardware resources available at a macromolecular crystallography beamline. Blu-Ice is a user interface that provides scientific experimenters and beamline support staff with intuitive graphical tools for collecting diffraction data and configuring beamlines for experiments. Blu-Ice communicates with the hardware at a beamline via DCS, an instrument-control and data-acquisition package designed to integrate hardware resources in a highly heterogeneous networked computing environment. Together, Blu-Ice and DCS provide a flexible platform for increasing the ease of use, the level of automation and the remote accessibility of beamlines. Blu-Ice and DCS are currently installed on four Stanford Synchrotron Radiation Laboratory crystallographic beamlines and are being implemented at sister light sources.
Similar articles
-
Software for the high-throughput collection of SAXS data using an enhanced Blu-Ice/DCS control system.J Synchrotron Radiat. 2010 Nov;17(6):774-81. doi: 10.1107/S0909049510028566. Epub 2010 Sep 3. J Synchrotron Radiat. 2010. PMID: 20975223 Free PMC article.
-
MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments.J Synchrotron Radiat. 2010 Sep;17(5):700-7. doi: 10.1107/S0909049510020005. Epub 2010 Jul 13. J Synchrotron Radiat. 2010. PMID: 20724792 Free PMC article.
-
Integrated instrumentation for combined polarized single-crystal XAS and diffraction data acquisition for biological applications.J Synchrotron Radiat. 2005 Jan;12(Pt 1):23-7. doi: 10.1107/S0909049504027839. Epub 2004 Dec 23. J Synchrotron Radiat. 2005. PMID: 15616361
-
Automation of macromolecular crystallography beamlines.Prog Biophys Mol Biol. 2005 Oct;89(2):124-52. doi: 10.1016/j.pbiomolbio.2004.09.003. Prog Biophys Mol Biol. 2005. PMID: 15910915 Review.
-
Application of in situ diffraction in high-throughput structure determination platforms.Methods Mol Biol. 2015;1261:233-53. doi: 10.1007/978-1-4939-2230-7_13. Methods Mol Biol. 2015. PMID: 25502203 Review.
Cited by
-
A common allele of HLA mediates asymptomatic SARS-CoV-2 infection.medRxiv [Preprint]. 2022 Oct 12:2021.05.13.21257065. doi: 10.1101/2021.05.13.21257065. medRxiv. 2022. Update in: Nature. 2023 Aug;620(7972):128-136. doi: 10.1038/s41586-023-06331-x PMID: 34031661 Free PMC article. Updated. Preprint.
-
Fragment-based screening by protein crystallography: successes and pitfalls.Int J Mol Sci. 2012 Oct 8;13(10):12857-79. doi: 10.3390/ijms131012857. Int J Mol Sci. 2012. PMID: 23202926 Free PMC article. Review.
-
The use of workflows in the design and implementation of complex experiments in macromolecular crystallography.Acta Crystallogr D Biol Crystallogr. 2012 Aug;68(Pt 8):975-84. doi: 10.1107/S090744491201863X. Epub 2012 Jul 17. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22868763 Free PMC article.
-
Analysis of substrate access to active sites in bacterial multicomponent monooxygenase hydroxylases: X-ray crystal structure of xenon-pressurized phenol hydroxylase from Pseudomonas sp. OX1.Biochemistry. 2011 Dec 27;50(51):11058-69. doi: 10.1021/bi201248b. Epub 2011 Dec 2. Biochemistry. 2011. PMID: 22136180 Free PMC article.
-
Open and shut: crystal structures of the dodecylmaltoside solubilized mechanosensitive channel of small conductance from Escherichia coli and Helicobacter pylori at 4.4 Å and 4.1 Å resolutions.Protein Sci. 2013 Apr;22(4):502-9. doi: 10.1002/pro.2222. Epub 2013 Feb 21. Protein Sci. 2013. PMID: 23339071 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous