In situ tetramer staining
- PMID: 12213340
- DOI: 10.1016/s0022-1759(02)00197-7
In situ tetramer staining
Abstract
The development of MHC tetramer staining has opened the doors to multiple avenues of new research [Science 274 (1996) 94]. In this review, we will discuss the development and application of in situ MHC tetramer (IST) staining. We describe two independently developed IST staining methodologies and discuss current uses, limitations, future uses and the interesting biology revealed by the use of IST staining.
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