Review
doi: 10.1038/nrm908.
Seven-transmembrane receptors
Affiliations
- PMID: 12209124
- DOI: 10.1038/nrm908
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Review
Seven-transmembrane receptors
Nat Rev Mol Cell Biol.
2002 Sep.
Abstract
Seven-transmembrane receptors, which constitute the largest, most ubiquitous and most versatile family of membrane receptors, are also the most common target of therapeutic drugs. Recent findings indicate that the classical models of G-protein coupling and activation of second-messenger-generating enzymes do not fully explain their remarkably diverse biological actions.
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