Review
doi: 10.1016/s1534-5807(02)00159-4.
Why FRET about Ran?
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- PMID: 11970885
- DOI: 10.1016/s1534-5807(02)00159-4
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Review
Why FRET about Ran?
Dev Cell.
2002 Apr.
Free article
Abstract
The Ran GTPase drives nucleocytoplasmic transport, stabilizes mitotic spindles, and catalyzes nuclear envelope formation. A unifying explanation of these functions is that RanGTP produces an organizing field or "atmosphere" around chromatin and acts as a spatial marker. This RanGTP field has now been visualized using fluorescent biosensors.
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