C-type lectin receptors on dendritic cells and Langerhans cells
- PMID: 11910898
- DOI: 10.1038/nri723
C-type lectin receptors on dendritic cells and Langerhans cells
Abstract
Dendritic cells and Langerhans cells are specialized for the recognition of pathogens and have a pivotal role in the control of immunity. As guardians of the immune system, they are present in essentially every organ and tissue, where they operate at the interface of innate and acquired immunity. Recently, several C-type lectin and lectin-like receptors have been characterized that are expressed abundantly on the surface of these professional antigen-presenting cells. It is now becoming clear that lectin receptors not only serve as antigen receptors but also regulate the migration of dendritic cells and their interaction with lymphocytes.
Similar articles
-
DC-SIGN, a C-type lectin on dendritic cells that unveils many aspects of dendritic cell biology.J Leukoc Biol. 2002 Jun;71(6):921-31. J Leukoc Biol. 2002. PMID: 12050176 Review.
-
C-type lectins on dendritic cells: key modulators for the induction of immune responses.Biochem Soc Trans. 2008 Dec;36(Pt 6):1478-81. doi: 10.1042/BST0361478. Biochem Soc Trans. 2008. PMID: 19021579 Review.
-
Dendritic cell immunoreceptors: C-type lectin receptors for pattern-recognition and signaling on antigen-presenting cells.J Dermatol Sci. 2007 Feb;45(2):77-86. doi: 10.1016/j.jdermsci.2006.09.001. Epub 2006 Oct 13. J Dermatol Sci. 2007. PMID: 17046204 Review.
-
How C-type lectins detect pathogens.Cell Microbiol. 2005 Apr;7(4):481-8. doi: 10.1111/j.1462-5822.2005.00506.x. Cell Microbiol. 2005. PMID: 15760448 Review.
-
Dendritic cell subsets and toll-like receptors.Handb Exp Pharmacol. 2008;(183):153-79. doi: 10.1007/978-3-540-72167-3_8. Handb Exp Pharmacol. 2008. PMID: 18071659 Review.
Cited by
-
CD69 does not affect the extent of T cell priming.PLoS One. 2012;7(10):e48593. doi: 10.1371/journal.pone.0048593. Epub 2012 Oct 30. PLoS One. 2012. PMID: 23119065 Free PMC article.
-
Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite.J Biol Chem. 2012 Feb 17;287(8):5756-63. doi: 10.1074/jbc.M111.312520. Epub 2011 Dec 28. J Biol Chem. 2012. PMID: 22205703 Free PMC article.
-
Maturation of function in dendritic cells for tolerance and immunity.J Cell Mol Med. 2005 Jul-Sep;9(3):643-54. doi: 10.1111/j.1582-4934.2005.tb00494.x. J Cell Mol Med. 2005. PMID: 16202211 Free PMC article. Review.
-
Streptococcus pneumoniae Impairs Maturation of Human Dendritic Cells and Consequent Activation of CD4+ T Cells via Pneumolysin.J Innate Immun. 2022;14(5):569-580. doi: 10.1159/000522339. Epub 2022 Mar 4. J Innate Immun. 2022. PMID: 35249041 Free PMC article.
-
Purified capsular polysaccharide of Neisseria meningitidis serogroup A as immune potentiator for antibody production.Curr Microbiol. 2010 Feb;60(2):79-84. doi: 10.1007/s00284-009-9505-9. Epub 2009 Sep 23. Curr Microbiol. 2010. PMID: 19771476
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials