Review
doi: 10.1038/415206a.
Seven-transmembrane-spanning receptors and heart function
Affiliations
- PMID: 11805844
- DOI: 10.1038/415206a
Item in Clipboard
Review
Seven-transmembrane-spanning receptors and heart function
Nature.
.
Abstract
Understanding precisely how the heart can recognize and respond to many different extracellular signalling molecules, such as neurotransmitters, hormones and growth factors, will aid the identification of new therapeutic targets through which cardiovascular diseases can be combated. In recent years, we have learned more about the complex interactions that occur between the receptors and the signalling pathways of the heart and its environment. Most of these discoveries have focused on the most common type of cardiac receptor - the seven-transmembrane-spanning receptor or G-protein-coupled receptor.
Similar articles
-
G protein-coupled receptor kinase: phosphorylation of muscarinic receptors and facilitation of receptor sequestration.Adv Pharmacol. 1996;36:173-91. doi: 10.1016/s1054-3589(08)60582-7. Adv Pharmacol. 1996. PMID: 8783560 Review. No abstract available.
-
Activation of a GTP-binding protein and a GTP-binding-protein-coupled receptor kinase (beta-adrenergic-receptor kinase-1) by a muscarinic receptor m2 mutant lacking phosphorylation sites.Eur J Biochem. 1994 Dec 1;226(2):267-76. doi: 10.1111/j.1432-1033.1994.tb20050.x. Eur J Biochem. 1994. PMID: 8001544
-
G-protein-coupled receptor function in heart failure.Cold Spring Harb Symp Quant Biol. 2002;67:439-44. doi: 10.1101/sqb.2002.67.439. Cold Spring Harb Symp Quant Biol. 2002. PMID: 12858569 Review. No abstract available.
-
Phosphorylation of G protein-coupled receptors: GPCR kinases in heart disease.Mol Interv. 2003 Aug;3(5):264-72. doi: 10.1124/mi.3.5.264. Mol Interv. 2003. PMID: 14993440 Review.
-
Diversity of structure, signaling and regulation within the family of muscarinic cholinergic receptors.FASEB J. 1992 Feb 1;6(3):845-52. FASEB J. 1992. PMID: 1740234 Review.
Cited by
-
The autonomic nervous system in septic shock and its role as a future therapeutic target: a narrative review.Ann Intensive Care. 2021 May 17;11(1):80. doi: 10.1186/s13613-021-00869-7. Ann Intensive Care. 2021. PMID: 33999297 Free PMC article. Review.
-
Prognosis of heart transplant patients in Mashhad University of Medical Sciences.Kardiochir Torakochirurgia Pol. 2020 Mar;17(1):33-38. doi: 10.5114/kitp.2020.94189. Epub 2020 Apr 7. Kardiochir Torakochirurgia Pol. 2020. PMID: 32728361 Free PMC article.
-
Inhibition of β1-AR/Gαs signaling promotes cardiomyocyte proliferation in juvenile mice through activation of RhoA-YAP axis.Elife. 2022 Dec 8;11:e74576. doi: 10.7554/eLife.74576. Elife. 2022. PMID: 36479975 Free PMC article.
-
Redundant catecholamine signaling consolidates fear memory via phospholipase C.J Neurosci. 2012 Feb 8;32(6):1932-41. doi: 10.1523/JNEUROSCI.5231-11.2012. J Neurosci. 2012. PMID: 22323706 Free PMC article.
-
G-protein coupled receptor resensitization-appreciating the balancing act of receptor function.Curr Mol Pharmacol. 2012 May 30. Online ahead of print. Curr Mol Pharmacol. 2012. PMID: 22697395 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
