Regression of pulmonary metastatic disease associated with intralesional BCG therapy of intracutaneous melanoma metastases
- PMID: 1175129
- DOI: 10.1002/1097-0142(197510)36:4<1305::aid-cncr2820360417>3.0.co;2-#
Regression of pulmonary metastatic disease associated with intralesional BCG therapy of intracutaneous melanoma metastases
Abstract
A 77-year-old white man with 64 intracutaneous melanoma metastases and a pulmonary metastatic deposit was treated with immunotherapy. Over an 8-month period, 17 intracutaneous lesions were inoculated with BCG. All 17 injected lesions and all 47 uninjected intracutaneous lesions resolved; no new nodules appeared and the pulmonary metastasis regressed (greater than 50%). This is the first documented case of a pulmonary metastatic focus responding to intralesional BCG therapy of intracutaneous metastases.
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