Membrane transport: ubiquitylation in endosomal sorting
- PMID: 11719242
- DOI: 10.1016/s0960-9822(01)00558-9
Membrane transport: ubiquitylation in endosomal sorting
Abstract
In yeast, membrane proteins from the biosynthetic and endocytic pathways must be ubiquitylated for sorting to inward-budding vesicles in late endosomes, which give rise to multivesicular bodies. A conserved protein complex containing the yeast Vps23p or its mammalian counterpart Tsg101 may act as the ubiquitin receptor.
Comment in
-
Membrane transport: a coat for ubiquitin.Curr Biol. 2002 Aug 6;12(15):R529-31. doi: 10.1016/s0960-9822(02)01030-8. Curr Biol. 2002. PMID: 12176377
Similar articles
-
Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking.Traffic. 2000 Mar;1(3):248-58. doi: 10.1034/j.1600-0854.2000.010307.x. Traffic. 2000. PMID: 11208108
-
Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae.J Cell Sci. 2003 May 15;116(Pt 10):1893-903. doi: 10.1242/jcs.00395. Epub 2003 Mar 18. J Cell Sci. 2003. PMID: 12668726
-
TSG101/mammalian VPS23 and mammalian VPS28 interact directly and are recruited to VPS4-induced endosomes.J Biol Chem. 2001 Apr 13;276(15):11735-42. doi: 10.1074/jbc.M009863200. Epub 2000 Dec 27. J Biol Chem. 2001. PMID: 11134028
-
Protein sorting into multivesicular endosomes.Curr Opin Cell Biol. 2003 Aug;15(4):446-55. doi: 10.1016/s0955-0674(03)00080-2. Curr Opin Cell Biol. 2003. PMID: 12892785 Review.
-
Insights from yeast endosomes.Curr Opin Cell Biol. 2002 Aug;14(4):454-62. doi: 10.1016/s0955-0674(02)00352-6. Curr Opin Cell Biol. 2002. PMID: 12383796 Review.
Cited by
-
Small glutamine-rich tetratricopeptide repeat-containing protein (SGT) interacts with the ubiquitin-dependent endocytosis (UbE) motif of the growth hormone receptor.Biochem J. 2003 Aug 1;373(Pt 3):855-63. doi: 10.1042/BJ20021591. Biochem J. 2003. PMID: 12735788 Free PMC article.
-
EhVps23: A Component of ESCRT-I That Participates in Vesicular Trafficking and Phagocytosis of Entamoeba histolytica.Front Cell Infect Microbiol. 2021 Oct 29;11:770759. doi: 10.3389/fcimb.2021.770759. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34778112 Free PMC article.
-
Involvement of the DNA repair protein hHR23 in p53 degradation.Mol Cell Biol. 2003 Dec;23(24):8960-9. doi: 10.1128/MCB.23.24.8960-8969.2003. Mol Cell Biol. 2003. PMID: 14645509 Free PMC article.
-
Genes and proteins for solute transport and sensing.Arabidopsis Book. 2002;1:e0092. doi: 10.1199/tab.0092. Epub 2002 Sep 30. Arabidopsis Book. 2002. PMID: 22303221 Free PMC article. No abstract available.
-
Configurational entropy in protein-peptide binding: computational study of Tsg101 ubiquitin E2 variant domain with an HIV-derived PTAP nonapeptide.J Mol Biol. 2009 Jun 5;389(2):315-35. doi: 10.1016/j.jmb.2009.04.003. Epub 2009 Apr 9. J Mol Biol. 2009. PMID: 19362095 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases