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Review
. 2001 Nov 13;11(22):R932-4.
doi: 10.1016/s0960-9822(01)00558-9.

Membrane transport: ubiquitylation in endosomal sorting

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Free article
Review

Membrane transport: ubiquitylation in endosomal sorting

S Dupré et al. Curr Biol. .
Free article

Abstract

In yeast, membrane proteins from the biosynthetic and endocytic pathways must be ubiquitylated for sorting to inward-budding vesicles in late endosomes, which give rise to multivesicular bodies. A conserved protein complex containing the yeast Vps23p or its mammalian counterpart Tsg101 may act as the ubiquitin receptor.

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