Review
doi: 10.1038/35036052.
Lipid rafts and signal transduction
Affiliations
- PMID: 11413487
- DOI: 10.1038/35036052
Item in Clipboard
Review
Lipid rafts and signal transduction
Nat Rev Mol Cell Biol.
2000 Oct.
Erratum in
- Nat Rev Mol Cell Biol 2001 Mar;2(3):216
Abstract
Signal transduction is initiated by complex protein-protein interactions between ligands, receptors and kinases, to name only a few. It is now becoming clear that lipid micro-environments on the cell surface -- known as lipid rafts -- also take part in this process. Lipid rafts containing a given set of proteins can change their size and composition in response to intra- or extracellular stimuli. This favours specific protein-protein interactions, resulting in the activation of signalling cascades.
Similar articles
-
Membrane microdomains, caveolae, and caveolar endocytosis of sphingolipids.Mol Membr Biol. 2006 Jan-Feb;23(1):101-10. doi: 10.1080/09687860500460041. Mol Membr Biol. 2006. PMID: 16611585 Review.
-
A role for lipid shells in targeting proteins to caveolae, rafts, and other lipid domains.Science. 2002 Jun 7;296(5574):1821-5. doi: 10.1126/science.1068886. Science. 2002. PMID: 12052946 Review.
-
[Cholesterol and lipid rafts in the biological membranes. Role in the release, reception and ion channel functions].Usp Fiziol Nauk. 2013 Jan-Mar;44(1):17-38. Usp Fiziol Nauk. 2013. PMID: 23662472 Review. Russian.
-
Relationship between cholesterol trafficking and signaling in rafts and caveolae.Biochim Biophys Acta. 2003 Mar 10;1610(2):219-28. doi: 10.1016/s0005-2736(03)00020-8. Biochim Biophys Acta. 2003. PMID: 12648776
-
Membrane cholesterol and the regulation of signal transduction.Biochem Soc Trans. 2004 Feb;32(Pt 1):65-9. doi: 10.1042/bst0320065. Biochem Soc Trans. 2004. PMID: 14748714 Review.
Cited by
-
Molecular mechanisms at the basis of the protective effect exerted by EPPS on neurodegeneration induced by prefibrillar amyloid oligomers.Sci Rep. 2024 Nov 3;14(1):26533. doi: 10.1038/s41598-024-77859-9. Sci Rep. 2024. PMID: 39489758 Free PMC article.
-
Temperature-Induced Seasonal Dynamics of Brain Gangliosides in Rainbow Trout (Oncorhynchus mykiss Walbaum) and Common Carp (Cyprinus carpio L.).Life (Basel). 2024 Oct 7;14(10):1273. doi: 10.3390/life14101273. Life (Basel). 2024. PMID: 39459573 Free PMC article.
-
Lipid rafts, caveolae, and epidermal growth factor receptor family: friends or foes?Cell Commun Signal. 2024 Oct 11;22(1):489. doi: 10.1186/s12964-024-01876-4. Cell Commun Signal. 2024. PMID: 39394159 Free PMC article. Review.
-
Mediating kinase activity in Ras-mutant cancer: potential for an individualised approach?Front Pharmacol. 2024 Sep 20;15:1441938. doi: 10.3389/fphar.2024.1441938. eCollection 2024. Front Pharmacol. 2024. PMID: 39372214 Free PMC article. Review.
-
Seroprevalence of Strongyloides stercoralis Infection in Patients with Hyperlipidemia: A Case-Control Study.Iran J Parasitol. 2024 Jul-Sep;19(3):341-348. doi: 10.18502/ijpa.v19i3.16394. Iran J Parasitol. 2024. PMID: 39318812 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
