Enhanced osteoclast-like cell functions on nanophase ceramics
- PMID: 11336305
- DOI: 10.1016/s0142-9612(00)00285-4
Enhanced osteoclast-like cell functions on nanophase ceramics
Abstract
Synthesis of tartrate-resistant acid phosphatase (TRAP) and formation of resorption pits by osteoclast-like cells, the bone-resorbing cells, on nanophase (that is, material formulations with grain sizes less than 100nm) alumina and hydroxyapatite (HA) were investigated in the present in vitro study. Compared to conventional (that is, grain sizes larger than 100 nm) ceramics, synthesis of TRAP was significantly greater in osteoclast-like cells cultured on nanophase alumina and on nanophase HA after 10 and 13 days, respectively. In addition, compared to conventional ceramics, formation of resorption pits was significantly greater by osteoclast-like cells cultured on nanophase alumina and on nanophase HA after 7, 10, and 13 days, respectively. The present study, therefore, demonstrated, for the first time, enhanced osteoclast-like cell function on ceramic surfaces with nanometer-size surface topography.
Similar articles
-
Enhanced functions of osteoblasts on nanophase ceramics.Biomaterials. 2000 Sep;21(17):1803-10. doi: 10.1016/s0142-9612(00)00075-2. Biomaterials. 2000. PMID: 10905463
-
Similar healthy osteoclast and osteoblast activity on nanocrystalline hydroxyapatite and nanoparticles of tri-calcium phosphate compared to natural bone.Int J Nanomedicine. 2014 Dec 2;9:5627-37. doi: 10.2147/IJN.S66852. eCollection 2014. Int J Nanomedicine. 2014. PMID: 25506216 Free PMC article.
-
[Experimental research on the effect of nanophase ceramics on osteoblasts functions].Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2005 Jun;22(3):463-7. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2005. PMID: 16013237 Chinese.
-
Specific proteins mediate enhanced osteoblast adhesion on nanophase ceramics.J Biomed Mater Res. 2000 Sep 5;51(3):475-83. doi: 10.1002/1097-4636(20000905)51:3<475::aid-jbm23>3.0.co;2-9. J Biomed Mater Res. 2000. PMID: 10880091
-
Tartrate-resistant acid phosphatase (TRAP) and the osteoclast/immune cell dichotomy.Autoimmunity. 2008 Apr;41(3):218-23. doi: 10.1080/08916930701694667. Autoimmunity. 2008. PMID: 18365835 Review.
Cited by
-
Enhancing Bioactivity and Mechanical Properties of Nano-Hydroxyapatite Derived from Oyster Shells through Hydrothermal Synthesis.Nanomaterials (Basel). 2024 Jul 30;14(15):1281. doi: 10.3390/nano14151281. Nanomaterials (Basel). 2024. PMID: 39120386 Free PMC article.
-
Investigation of Surface Layers on Biological and Synthetic Hydroxyapatites Based on Bone Mineralization Process.Biomimetics (Basel). 2023 Apr 28;8(2):184. doi: 10.3390/biomimetics8020184. Biomimetics (Basel). 2023. PMID: 37218770 Free PMC article. Review.
-
In vitro angiogenesis in response to biomaterial properties for bone tissue engineering: a review of the state of the art.Regen Biomater. 2023 Mar 27;10:rbad027. doi: 10.1093/rb/rbad027. eCollection 2023. Regen Biomater. 2023. PMID: 37081860 Free PMC article. Review.
-
Corrosion of Stirred Electrochemical Nano-Crystalline Hydroxyapatite (HA) Coatings on Ti6Al4V.Materials (Basel). 2022 Dec 2;15(23):8609. doi: 10.3390/ma15238609. Materials (Basel). 2022. PMID: 36500105 Free PMC article.
-
Roles of osteoclasts in alveolar bone remodeling.Genesis. 2022 Sep;60(8-9):e23490. doi: 10.1002/dvg.23490. Epub 2022 Jun 27. Genesis. 2022. PMID: 35757898 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
