Three ways to make a vesicle
- PMID: 11252894
- DOI: 10.1038/35043117
Three ways to make a vesicle
Erratum in
- Nat Rev Mol Cell Biol 2001 Mar;2(3):216
Abstract
Cargo molecules have to be included in carrier vesicles of different forms and sizes to be transported between organelles. During this process, a limited set of proteins, including the coat proteins COPI, COPII and clathrin, carries out a programmed set of sequential interactions that lead to the budding of vesicles. A general model to explain the formation of coated vesicles is starting to emerge but the picture is more complex than we had imagined.
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