doi: 10.1038/35057011.
Expressing the human genome
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- PMID: 11237001
- DOI: 10.1038/35057011
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Expressing the human genome
Nature.
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Abstract
We have searched the human genome for genes encoding new proteins that may be involved in three nuclear gene expression processes: transcription, pre-messenger RNA splicing and polyadenylation. A plethora of potential new factors are implicated by sequence in nuclear gene expression, revealing a substantial but selective increase in complexity compared with Drosophila melanogaster and Caenorhabditis elegans. Although the raw genomic information has limitations, its availability offers new experimental approaches for studying gene expression.
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