Review
doi: 10.1016/s0966-842x(00)01823-0.
The role of cationic antimicrobial peptides in innate host defences
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- PMID: 10989307
- DOI: 10.1016/s0966-842x(00)01823-0
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Review
The role of cationic antimicrobial peptides in innate host defences
Trends Microbiol.
2000 Sep.
Abstract
Cationic antimicrobial peptides are found in all living species. A single animal can contain >24 different antimicrobial peptides, which fall into four structural classes. These peptides are produced in large quantities at sites of infection and/or inflammation and can have broad-spectrum antibacterial, antifungal, antiviral, antiprotozoan and antisepsis properties. In addition, they interact directly with host cells to modulate the inflammatory process and innate defences.
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