Review
doi: 10.1016/s0959-440x(00)00105-6.
Recent advances in structure-based rational drug design
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- PMID: 10981625
- DOI: 10.1016/s0959-440x(00)00105-6
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Review
Recent advances in structure-based rational drug design
Curr Opin Struct Biol.
2000 Aug.
Abstract
Two approaches to structure-based drug design, that is, the docking of known compounds into a target protein and molecular assembly in situ, are seen to be merging technologies. The need for structural information about drug-protein complexes is now fundamental for drug discovery.
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