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Review
. 2000 Mar 29;355(1395):391-400.
doi: 10.1098/rstb.2000.0579.

T-cell memory: lessons from Epstein-Barr virus infection in man

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Review

T-cell memory: lessons from Epstein-Barr virus infection in man

A B Rickinson et al. Philos Trans R Soc Lond B Biol Sci. .

Abstract

Epstein-Barr virus offers an ideal opportunity to follow the human T-cell response to a virus infection over time from its acute primary phase, as seen in infectious mononucleosis patients, into the memory phase that accompanies life-long virus persistence. Here we review recent evidence on the development and maturation of cytotoxic T-cell memory using this viral system.

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