T-cell memory: lessons from Epstein-Barr virus infection in man
- PMID: 10794060
- PMCID: PMC1692739
- DOI: 10.1098/rstb.2000.0579
T-cell memory: lessons from Epstein-Barr virus infection in man
Abstract
Epstein-Barr virus offers an ideal opportunity to follow the human T-cell response to a virus infection over time from its acute primary phase, as seen in infectious mononucleosis patients, into the memory phase that accompanies life-long virus persistence. Here we review recent evidence on the development and maturation of cytotoxic T-cell memory using this viral system.
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