The application of DNA microarrays in gene expression analysis
- PMID: 10751688
- DOI: 10.1016/s0168-1656(00)00204-2
The application of DNA microarrays in gene expression analysis
Abstract
DNA microarray technology is a new and powerful technology that will substantially increase the speed of molecular biological research. This paper gives a survey of DNA microarray technology and its use in gene expression studies. The technical aspects and their potential improvements are discussed. These comprise array manufacturing and design, array hybridisation, scanning, and data handling. Furthermore, it is discussed how DNA microarrays can be applied in the working fields of: safety, functionality and health of food and gene discovery and pathway engineering in plants.
Similar articles
-
Position of the American Dietetic Association: biotechnology and the future of food.J Am Diet Assoc. 1995 Dec;95(12):1429-32. doi: 10.1016/s0002-8223(95)00376-2. J Am Diet Assoc. 1995. PMID: 7594149 Review. No abstract available.
-
Plant cell walls as targets for biotechnology.Curr Opin Plant Biol. 1998 Apr;1(2):179-85. doi: 10.1016/s1369-5266(98)80022-8. Curr Opin Plant Biol. 1998. PMID: 10066576 Review.
-
Ending world hunger. The promise of biotechnology and the threat of antiscience zealotry.Plant Physiol. 2000 Oct;124(2):487-90. doi: 10.1104/pp.124.2.487. Plant Physiol. 2000. PMID: 11027697 Free PMC article. No abstract available.
-
DNA microarray technology and application.Med Sci Monit. 2000 Jul-Aug;6(4):796-800. Med Sci Monit. 2000. PMID: 11208413 Review.
-
Application of DNA microarrays in occupational health research.J Occup Health. 2004 Jan;46(1):20-5. doi: 10.1539/joh.46.20. J Occup Health. 2004. PMID: 14960826 Review.
Cited by
-
Dipyrrylmetheneboron difluorides as labels in two-photon excited fluorometry. Part II--Nucleic acid hybridization assays.J Fluoresc. 2005 May;15(3):233-42. doi: 10.1007/s10895-005-2623-2. J Fluoresc. 2005. PMID: 15986150
-
Combined transcript and metabolite analysis reveals genes involved in spider mite induced volatile formation in cucumber plants.Plant Physiol. 2004 Aug;135(4):2012-24. doi: 10.1104/pp.104.048116. Epub 2004 Aug 13. Plant Physiol. 2004. PMID: 15310834 Free PMC article.
-
Application of four dyes in gene expression analyses by microarrays.BMC Genomics. 2005 Jul 25;6:101. doi: 10.1186/1471-2164-6-101. BMC Genomics. 2005. PMID: 16042794 Free PMC article.
-
cDNA microarray analysis of cyclosporin A (CsA)-treated human peripheral blood mononuclear cells reveal modulation of genes associated with apoptosis, cell-cycle regulation and DNA repair.Mol Cell Biochem. 2007 Oct;304(1-2):235-41. doi: 10.1007/s11010-007-9505-7. Epub 2007 May 30. Mol Cell Biochem. 2007. PMID: 17534698
-
Expression of proteins associated with adipocyte lipolysis was significantly changed in the adipose tissues of the obese spontaneously hypertensive/NDmcr-cp rat.Diabetol Metab Syndr. 2014 Jan 27;6(1):8. doi: 10.1186/1758-5996-6-8. Diabetol Metab Syndr. 2014. PMID: 24468282 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources