Review
doi: 10.1016/s1286-4579(00)00267-7.
Turning a corner on HIV neutralization?
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- PMID: 10742693
- DOI: 10.1016/s1286-4579(00)00267-7
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Review
Turning a corner on HIV neutralization?
Microbes Infect.
2000 Feb.
Free article
Abstract
HIV vaccine development has been hampered by the inability of conventional immunogens to elicit antibodies capable of neutralizing primary isolates of the virus. Recent studies using 'fusion-competent' immunogens that capture transitional intermediate structures of the functioning envelope protein suggest that this goal may now be achievable.
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