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Comparative Study
. 2000 Mar;38(3):1247-9.
doi: 10.1128/JCM.38.3.1247-1249.2000.

Use of calibrated viral load standards for group M subtypes of human immunodeficiency virus type 1 to assess the performance of viral RNA quantitation tests

L L Jagodzinski  1 , D L Wiggins, J L McManis, S Emery, J Overbaugh, M Robb, S Bodrug, N L Michael
Affiliations
Comparative Study

Use of calibrated viral load standards for group M subtypes of human immunodeficiency virus type 1 to assess the performance of viral RNA quantitation tests

L L Jagodzinski et al. J Clin Microbiol. 2000 Mar.

Abstract

Optimal management of human immunodeficiency virus type 1 (HIV-1) disease requires accurate quantitation of viral RNA concentrations in plasma. Evidence for increasing geographic intermixing of HIV-1 subtypes makes equivalent quantitation of all subtypes essential. The performances of six quantitative viral RNA tests are described, for the first time, with calibrated viral isolates of diverse subtypes.

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References

    1. Alaeus A, Leitner T, Lidman K, Albert J. Most HIV-1 genetic subtypes have entered Sweden. AIDS. 1997;11:199–202. - PubMed
    1. Alaeus A, Lidman K, Sonnerborg A, Albert J. Subtype-specific problems with quantification of plasma HIV-1 RNA. AIDS. 1997;11:859–865. - PubMed
    1. Bodrug S, Domingo R, Holloway J, Sanders M, Nunomura K, Sloan C, Billyard B. Gen-probe single-tube quantitative HIV assay. J Clin Microbiol Infect. 1997;3:1050.
    1. Brambilla D, Leung S, Lew J, Todd J, Herman S, Cronin M, Shapiro D E, Bremer J, Hanson C, Hillyer G V, McSherry G D, Sperling R S, Coombs R W, Reichelderfer P S. Absolute copy number and relative change in determinations of human immunodeficiency virus type 1 RNA in plasma: effect of an external standard on kit comparisons. J Clin Microbiol. 1998;36:311–314. - PMC - PubMed
    1. Brodine S K, Shaffer R A, Starkey M J, Tasker S A, Gilcrest J L, Louder M K, Barile A, VanCott T C, Vahey M T, McCutchan F E, Birx D L, Richman D D, Mascola J R. Drug resistance patterns, genetic subtypes, clinical features and risk factors in military personnel with HIV-1 seroconversion. Ann Intern Med. 1999;131:502–506. - PubMed

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