Resolution of the pathways of poliovirus type 1 transmission during an outbreak
- PMID: 10698978
- PMCID: PMC86309
- DOI: 10.1128/JCM.38.3.945-952.2000
Resolution of the pathways of poliovirus type 1 transmission during an outbreak
Abstract
An outbreak of poliomyelitis with 20 cases occurred in Israel, Gaza, and the West Bank from October 1987 to October 1988. The wild type 1 poliovirus associated with the outbreak was most closely related to viruses found in the Nile Delta. The epidemiologic links among patients involved in the outbreak and patients with community-acquired infections during the outbreak were inferred from the evolutionary relationships among isolates of the outbreak virus. Complete VP1 sequences (906 nucleotides) were determined for 12 clinical and 4 sewage isolates. A total of 58 nucleotide differences were found among the 16 isolates; 74% of all substitutions were synonymous third-position transitions. An evolutionary tree, representing both the pathways of VP1 sequence evolution and the inferred chains of virus transmission during the outbreak, was constructed under the assumption that each substitution had occurred only once. The combined epidemiologic and molecular data suggest that a single founder strain was introduced into Israel from the vicinity of Gaza in the fall of 1987. Poliovirus circulation was apparently localized to southern communities during the winter and spread north by the following summer into the Hadera subdistrict of Israel, where it radiated via multiple chains of transmission into other communities in northern Israel and the West Bank. The close sequence matches (>99%) between clinical and sewage isolates from the same communities confirm the utility of environmental sampling as a tool for monitoring wild poliovirus circulation.
Figures
Similar articles
-
Molecular epidemiology of silent introduction and sustained transmission of wild poliovirus type 1, Israel, 2013.Euro Surveill. 2014 Feb 20;19(7):20709. doi: 10.2807/1560-7917.es2014.19.7.20709. Euro Surveill. 2014. PMID: 24576471
-
Molecular characterization of a wild poliovirus type 3 epidemic in The Netherlands (1992 and 1993).J Clin Microbiol. 1995 Dec;33(12):3252-6. doi: 10.1128/jcm.33.12.3252-3256.1995. J Clin Microbiol. 1995. PMID: 8586711 Free PMC article.
-
Molecular detection of an importation of type 3 wild poliovirus into Canada from The Netherlands in 1993.Appl Environ Microbiol. 1997 Feb;63(2):519-23. doi: 10.1128/aem.63.2.519-523.1997. Appl Environ Microbiol. 1997. PMID: 9023931 Free PMC article.
-
Poliomyelitis control in Israel, the West Bank and Gaza Strip: changing strategies with the goal of eradication in an endemic area.Bull World Health Organ. 1994;72(5):783-96. Bull World Health Organ. 1994. PMID: 7955030 Free PMC article. Review.
-
Laboratory challenges in response to silent introduction and sustained transmission of wild poliovirus type 1 in Israel during 2013.J Infect Dis. 2014 Nov 1;210 Suppl 1:S304-14. doi: 10.1093/infdis/jiu294. J Infect Dis. 2014. PMID: 25316849 Review.
Cited by
-
Epidemiology of Type 3 Poliovirus AFP Cases in Israel between 1973 and 1988: Whole Genome Sequencing of RNA Extracted Directly from Archived Stocks to Avoid Re-Culturing Neurovirulent Wild Poliovirus.Vaccines (Basel). 2022 Dec 15;10(12):2154. doi: 10.3390/vaccines10122154. Vaccines (Basel). 2022. PMID: 36560563 Free PMC article.
-
Assessing the stability of polio eradication after the withdrawal of oral polio vaccine.PLoS Biol. 2018 Apr 27;16(4):e2002468. doi: 10.1371/journal.pbio.2002468. eCollection 2018 Apr. PLoS Biol. 2018. PMID: 29702638 Free PMC article.
-
Insights from a Systematic Search for Information on Designs, Costs, and Effectiveness of Poliovirus Environmental Surveillance Systems.Food Environ Virol. 2017 Dec;9(4):361-382. doi: 10.1007/s12560-017-9314-4. Epub 2017 Jul 7. Food Environ Virol. 2017. PMID: 28687986 Free PMC article. Review.
-
Molecular and Phenotypic Characterization of a Highly Evolved Type 2 Vaccine-Derived Poliovirus Isolated from Seawater in Brazil, 2014.PLoS One. 2016 Mar 28;11(3):e0152251. doi: 10.1371/journal.pone.0152251. eCollection 2016. PLoS One. 2016. PMID: 27019095 Free PMC article.
-
Modeling options to manage type 1 wild poliovirus imported into Israel in 2013.J Infect Dis. 2015 Jun 1;211(11):1800-12. doi: 10.1093/infdis/jiu674. Epub 2014 Dec 10. J Infect Dis. 2015. PMID: 25505296 Free PMC article.
References
-
- Afif H, Sutter R W, Fontaine R E, Kew O M, Pallansch M A, Goyal M K, Cochi S L. Outbreak of poliomyelitis in Gizan, Saudi Arabia: co-circulation of wild type 1 polioviruses from three separate origins. J Infect Dis. 1997;175(Suppl. 1):S71–S75. - PubMed
-
- Alexander J P, Jr, Alemu W, Kilpatrick D, Kebede S, Yang C-F, Beyene H, Kew O M. Poliomyelitis in Ethiopia: virologic links to poliomyelitis cases in the Indian subcontinent. Pediatr Infect Dis J. 1996;15:629–631. - PubMed
-
- Centers for Disease Control and Prevention. Virologic surveillance and progress toward poliomyelitis eradication—Eastern Mediterranean Region, 1995–September 1998. Morbid Mortal Weekly Rep. 1998;47:1001–1005. - PubMed
-
- Dahling D R, Berg G, Berman D. BGM, a continuous cell line more sensitive than primary rhesus and African green kidney cells for the recovery of viruses from water. Health Lab Sci. 1974;11:275–282. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical