Review
doi: 10.1038/70928.
Clinical applications of angiogenic growth factors and their inhibitors
Affiliations
- PMID: 10581076
- DOI: 10.1038/70928
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Review
Clinical applications of angiogenic growth factors and their inhibitors
Nat Med.
1999 Dec.
Abstract
Promoting the formation of new collateral vessels in ischemic tissues using angiogenic growth factors (therapeutic angiogenesis) is a an exciting frontier of cardiovascular medicine. Conversely, inhibition of the action of key regulators of angiogenesis, such as VEGF, constitutes a promising approach for the treatment of solid tumors and intraocular neovascular syndromes. These concepts are being tested now in clinical trials.
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