Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 Oct;11(10):729-35.
doi: 10.1006/cyto.1999.0485.

FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4

M H Xie  1 , I Holcomb, B Deuel, P Dowd, A Huang, A Vagts, J Foster, J Liang, J Brush, Q Gu, K Hillan, A Goddard, A L Gurney
Affiliations

FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4

M H Xie et al. Cytokine. 1999 Oct.

Abstract

We have identified a novel fibroblast growth factor, FGF-19, the most distant member of the FGF family described to date. FGF-19 is a high affinity, heparin dependent ligand for FGFR4 and is the first member of the FGF family to show exclusive binding to FGFR4. Human FGF-19 maps to chromosome 11 q13.1, a region associated with an osteoporosis-pseudoglioma syndrome of skeletal and retinal defects. FGF-19 message is expressed in several tissues including fetal cartilage, skin, and retina, as well as adult gall bladder and is overexpressed in a colon adenocarcinoma cell line.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

MeSH terms

Associated data