Review
doi: 10.1006/scdb.1999.0298.
Histone acetyltransferase complexes
Affiliations
- PMID: 10441070
- DOI: 10.1006/scdb.1999.0298
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Review
Histone acetyltransferase complexes
Semin Cell Dev Biol.
1999 Apr.
Abstract
Modification of histone amino terminal tails by acetylation has long been linked to the transcriptional capacity of genes in chromatin and to various aspects of chromatin dynamics. Over the last few years a flurry of reports have described the purification and identification of a large number of histone acetyltransferases. Many of these enzymes had previously been described as transcriptional regulators and have frequently been isolated as part of larger multisubunit protein complexes. This review describes the association of acetyltransferases with partner proteins and the additional functional attributes of such complexes beyond catalytic function.
Copyright 1999 Academic Press.
Comment in
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Introduction: chromatin--a target for intracellular signalling pathways.Semin Cell Dev Biol. 1999 Apr;10(2):165-7. doi: 10.1006/scdb.1999.0297. Semin Cell Dev Biol. 1999. PMID: 10441069 No abstract available.
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