Transmission electron microscopy studies of Moraxella (Branhamella) catarrhalis
- PMID: 10030548
- DOI: 10.1111/j.1574-695X.1999.tb01717.x
Transmission electron microscopy studies of Moraxella (Branhamella) catarrhalis
Abstract
A trypsin-sensitive 200-kDa protein has been reported to be exclusively associated with haemagglutinating isolates of Moraxella (Branhamella) catarrhalis. Transmission electron microscopy studies revealed that haemagglutination by M. catarrhalis to both human and rabbit erythrocytes was mediated by a trypsin-sensitive outer fibrillar coat. This fibrillar layer was absent on non-haemagglutinating isolates examined. Immuno-electron microscopy, using a polyclonal antiserum containing antibodies to the 200-kDa protein as a probe, showed that the 200-kDa protein is present on the outer fibrillar layer of the bacterium. These findings suggest that the haemagglutinin of M. catarrhalis is a 200-kDa protein present on the outer fibrillar coat.
Similar articles
-
Haemagglutination properties of Moraxella (Branhamella) catarrhalis.Br J Biomed Sci. 1996 Dec;53(4):257-62. Br J Biomed Sci. 1996. PMID: 9069102
-
A 200 kDa protein is associated with haemagglutinating isolates of Moraxella (Branhamella) catarrhalis.FEMS Immunol Med Microbiol. 1997 Jul;18(3):209-16. doi: 10.1111/j.1574-695X.1997.tb01047.x. FEMS Immunol Med Microbiol. 1997. PMID: 9271172
-
Tissue culture adherence and haemagglutination characteristics of Moraxella (Branhamella) catarrhalis.FEMS Immunol Med Microbiol. 1999 May;24(1):105-14. doi: 10.1111/j.1574-695X.1999.tb01271.x. FEMS Immunol Med Microbiol. 1999. PMID: 10340719
-
Pili (fimbriae) of Branhamella species.Am J Med. 1990 May 14;88(5A):36S-40S. doi: 10.1016/0002-9343(90)90260-k. Am J Med. 1990. PMID: 1971156 Review.
-
Moraxella (Branhamella) catarrhalis bacteremia. A case report and literature review.Arch Intern Med. 1990 Jun;150(6):1332-4. Arch Intern Med. 1990. PMID: 2112907 Review.
Cited by
-
The Hag protein of Moraxella catarrhalis strain O35E is associated with adherence to human lung and middle ear cells.Infect Immun. 2003 Sep;71(9):4977-84. doi: 10.1128/IAI.71.9.4977-4984.2003. Infect Immun. 2003. PMID: 12933840 Free PMC article.
-
A hag mutant of Moraxella catarrhalis strain O35E is deficient in hemagglutination, autoagglutination, and immunoglobulin D-binding activities.Infect Immun. 2002 Aug;70(8):4523-33. doi: 10.1128/IAI.70.8.4523-4533.2002. Infect Immun. 2002. PMID: 12117964 Free PMC article.
-
The Moraxella catarrhalis porin-like outer membrane protein CD is an adhesin for human lung cells.Infect Immun. 2004 Apr;72(4):1906-13. doi: 10.1128/IAI.72.4.1906-1913.2004. Infect Immun. 2004. PMID: 15039309 Free PMC article.
-
The UspA1 protein and a second type of UspA2 protein mediate adherence of Moraxella catarrhalis to human epithelial cells in vitro.J Bacteriol. 2000 Mar;182(5):1364-73. doi: 10.1128/JB.182.5.1364-1373.2000. J Bacteriol. 2000. PMID: 10671460 Free PMC article.
-
Identification of a Moraxella catarrhalis outer membrane protein exhibiting both adhesin and lipolytic activities.Infect Immun. 2003 Aug;71(8):4341-50. doi: 10.1128/IAI.71.8.4341-4350.2003. Infect Immun. 2003. PMID: 12874311 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
