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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 9
2012 1
2016 1
2017 9
2018 54
2019 1451
2020 11399
2021 44
2022 5
2024 0

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11,399 results

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Page 1
Role of RNA modifications in cancer.
Barbieri I, Kouzarides T. Barbieri I, et al. Nat Rev Cancer. 2020 Jun;20(6):303-322. doi: 10.1038/s41568-020-0253-2. Epub 2020 Apr 16. Nat Rev Cancer. 2020. PMID: 32300195 Review.
Many of the enzymes responsible for regulating protein and DNA modifications are targets of current cancer therapies. RNA epitranscriptomics, the study of RNA modifications, is the new frontier of this arena. ...Increasing evidence suggests that RNA modification pathways a …
Many of the enzymes responsible for regulating protein and DNA modifications are targets of current cancer therapies. RNA epitranscri …
Memory CD8(+) T cell responses to cancer.
Han J, Khatwani N, Searles TG, Turk MJ, Angeles CV. Han J, et al. Semin Immunol. 2020 Jun;49:101435. doi: 10.1016/j.smim.2020.101435. Epub 2020 Nov 30. Semin Immunol. 2020. PMID: 33272898 Free PMC article. Review.
Studies over the past two decades have identified four subsets of memory CD8(+) T cells - central, effector, stem-like, and tissue resident memory - that either circulate through blood, lymphoid and peripheral organs, or reside in tissues where cancers develop. In this art …
Studies over the past two decades have identified four subsets of memory CD8(+) T cells - central, effector, stem-like, and tissue resident …
Emerging Mechanisms and Disease Relevance of Ferroptosis.
Stockwell BR, Jiang X, Gu W. Stockwell BR, et al. Trends Cell Biol. 2020 Jun;30(6):478-490. doi: 10.1016/j.tcb.2020.02.009. Epub 2020 Mar 21. Trends Cell Biol. 2020. PMID: 32413317 Free PMC article. Review.
Cell death is an essential feature of development in multicellular organisms, a critical driver of degenerative diseases, and can be harnessed for treating some cancers. Understanding the mechanisms governing cell death is critical for addressing its role in disease. ...
Cell death is an essential feature of development in multicellular organisms, a critical driver of degenerative diseases, and can be harness …
Review of precision cancer medicine: Evolution of the treatment paradigm.
Tsimberidou AM, Fountzilas E, Nikanjam M, Kurzrock R. Tsimberidou AM, et al. Cancer Treat Rev. 2020 Jun;86:102019. doi: 10.1016/j.ctrv.2020.102019. Epub 2020 Mar 31. Cancer Treat Rev. 2020. PMID: 32251926 Free PMC article. Review.
The majority of these trials demonstrated that matched therapy is associated with superior outcomes compared to non-matched therapy across tumor types and in specific cancers. To improve the implementation of precision medicine, this approach should be used early in the co …
The majority of these trials demonstrated that matched therapy is associated with superior outcomes compared to non-matched therapy across t …
Exploiting the folate receptor α in oncology.
Scaranti M, Cojocaru E, Banerjee S, Banerji U. Scaranti M, et al. Nat Rev Clin Oncol. 2020 Jun;17(6):349-359. doi: 10.1038/s41571-020-0339-5. Epub 2020 Mar 9. Nat Rev Clin Oncol. 2020. PMID: 32152484 Review.
Binding to FRalpha is one of several methods by which folate is taken up by cells; however, this receptor is an attractive anticancer drug target owing to the overexpression of FRalpha in a range of solid tumours, including ovarian, lung and breast cancers. Furthermore, us …
Binding to FRalpha is one of several methods by which folate is taken up by cells; however, this receptor is an attractive anticancer drug t …
Tertiary lymphoid structures in cancer - considerations for patient prognosis.
Munoz-Erazo L, Rhodes JL, Marion VC, Kemp RA. Munoz-Erazo L, et al. Cell Mol Immunol. 2020 Jun;17(6):570-575. doi: 10.1038/s41423-020-0457-0. Epub 2020 May 15. Cell Mol Immunol. 2020. PMID: 32415259 Free PMC article. Review.
They share structural and functional characteristics with secondary lymphoid structures such as lymph nodes and can contain B-cell follicles and germinal centers surrounded by a T-cell region. TLS have been described in several types of cancers and are usually associated w …
They share structural and functional characteristics with secondary lymphoid structures such as lymph nodes and can contain B-cell follicles …
The relevance of nutrition to pediatric oncology: A cancer control perspective.
Rogers PC, Barr RD. Rogers PC, et al. Pediatr Blood Cancer. 2020 Jun;67 Suppl 3:e28213. doi: 10.1002/pbc.28213. Epub 2020 Feb 25. Pediatr Blood Cancer. 2020. PMID: 32096351 Review.
The science of nutrigenomics, nutrigenetics, and bioactive foods (phytochemicals), and how nutrition affects cancer biology and cancer treatment, is growing. Nutritional epigenetics is giving us an understanding that there are possible primary prevention strategies …
The science of nutrigenomics, nutrigenetics, and bioactive foods (phytochemicals), and how nutrition affects cancer biology and ca …
Immunoscore and its introduction in clinical practice.
Galon J, Lanzi A. Galon J, et al. Q J Nucl Med Mol Imaging. 2020 Jun;64(2):152-161. doi: 10.23736/S1824-4785.20.03249-5. Epub 2020 Feb 27. Q J Nucl Med Mol Imaging. 2020. PMID: 32107902 Free article. Review.
Current cancer classification is based on intrinsic tumor parameters such as characteristic of tumor cells, tumor progression, tumor invasion and the presence of distant metastases, as summarized by the AJCC/UICC-TNM stratification system. There is currently no immune-base …
Current cancer classification is based on intrinsic tumor parameters such as characteristic of tumor cells, tumor progression, tumor …
Primary Liver Cancers: Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma.
Mejia JC, Pasko J. Mejia JC, et al. Surg Clin North Am. 2020 Jun;100(3):535-549. doi: 10.1016/j.suc.2020.02.013. Epub 2020 Apr 16. Surg Clin North Am. 2020. PMID: 32402299 Review.
The incidence of liver cancers has continued to increase over the past few decades and mortality related to liver cancer has increased by more than 2% annually since 2007. This article reviews the essential workup and treatment options necessary for general surgeons …
The incidence of liver cancers has continued to increase over the past few decades and mortality related to liver cancer has i …
Lineage plasticity in cancer: a shared pathway of therapeutic resistance.
Quintanal-Villalonga Á, Chan JM, Yu HA, Pe'er D, Sawyers CL, Sen T, Rudin CM. Quintanal-Villalonga Á, et al. Nat Rev Clin Oncol. 2020 Jun;17(6):360-371. doi: 10.1038/s41571-020-0340-z. Epub 2020 Mar 9. Nat Rev Clin Oncol. 2020. PMID: 32152485 Free PMC article. Review.
Tumour cell conversion into a different histological subtype has been associated with a loss of dependency on the original oncogenic driver, leading to therapeutic resistance. A well-known pathway of lineage plasticity in cancer - the histological transformation of adenoca …
Tumour cell conversion into a different histological subtype has been associated with a loss of dependency on the original oncogenic driver, …
11,399 results
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