Clonal origin of pituitary adenomas.
J Clin Endocrinol Metab. 1990.
PMID: 1977759
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Clonal origin of pituitary adenomas.
J Neurosurg. 1990.
PMID: 2213163
Search results
Page 1
Clonal origin of pituitary adenomas.
J Clin Endocrinol Metab. 1990 Dec;71(6):1427-33. doi: 10.1210/jcem-71-6-1427.
J Clin Endocrinol Metab. 1990.
PMID: 1977759
As the pathogenesis of pituitary adenomas remains unclear, the tumor clonal composition of these common neoplasms was studied. ...A mixed plurihormonal adenoma was polyclonal, as were 2 tumors consisting of adenomatous lactotrophs interspersed with non …
As the pathogenesis of pituitary adenomas remains unclear, the tumor clonal composition of these common neoplasms …
Clonal origin of pituitary adenomas.
J Neurosurg. 1990 Nov;73(5):731-5. doi: 10.3171/jns.1990.73.5.0731.
J Neurosurg. 1990.
PMID: 2213163
Benign pituitary adenomas are among the most common neurosurgical tumors and account for a diversity of clinical syndromes due to their hormone content and release. To determine whether these tumors arise from a single cell or multiple cells, the authors studied X c …
Benign pituitary adenomas are among the most common neurosurgical tumors and account for a diversity of clinical syndromes due …
Gonadotropinomas.
Semin Reprod Med. 2002 Nov;20(4):339-48. doi: 10.1055/s-2002-36708.
Semin Reprod Med. 2002.
PMID: 12536357
Review.
Advances in immunocytochemistry, electron microscopy, cell culture, and molecular techniques have demonstrated that 80 to 90% of the clinically nonfunctioning pituitary adenomas are gonadotrope-derived and recently recognized as gonadotropinomas, which account for a …
Advances in immunocytochemistry, electron microscopy, cell culture, and molecular techniques have demonstrated that 80 to 90% of the clinica …
[Classification and pathophysiology of pituitary adenomas].
Bull Acad Natl Med. 2009 Oct;193(7):1543-56; discussion 1556.
Bull Acad Natl Med. 2009.
PMID: 20669635
Review.
French.
Pituitary adenomas are benign tumors that can be classified according to the type of hormone they produce, immunocytochemical characteristics (which generally confirm the clinical classification) or, as proposed by WHO in 2004, specific differentiation markers of th …
Pituitary adenomas are benign tumors that can be classified according to the type of hormone they produce, immunocytochemical …
Clonal origins of adrenocorticotropin-secreting pituitary tissue in Cushing's disease.
J Clin Endocrinol Metab. 1992 Nov;75(5):1303-9. doi: 10.1210/jcem.75.5.1358909.
J Clin Endocrinol Metab. 1992.
PMID: 1358909
It is unclear whether Cushing's disease results from a primary pituitary disorder or arises in response to abnormal hypothalamic control of the pituitary gland. ...We used X-linked restriction fragment length polymorphisms at the phosphoglycerate kinase, hypoxanthin …
It is unclear whether Cushing's disease results from a primary pituitary disorder or arises in response to abnormal hypothalamic cont …
Genesis of pituitary adenomas: state of the art.
J Neurooncol. 2001 Sep;54(2):95-110. doi: 10.1023/a:1012988828164.
J Neurooncol. 2001.
PMID: 11761437
Review.
In recent years, remarkable progress has been made in the understanding of the pathogenesis of pituitary tumors. Pituitary tumors originate from the uncontrolled proliferation of a single transformed cell in which an initiating event has caused a gain of prol …
In recent years, remarkable progress has been made in the understanding of the pathogenesis of pituitary tumors. Pituitary tum …
The role of the GH/IGF system in pituitary tumorigenesis.
Horm Metab Res. 2003 Nov-Dec;35(11-12):664-6. doi: 10.1055/s-2004-814165.
Horm Metab Res. 2003.
PMID: 14710344
Review.
Pituitary adenomas are mostly benign tumours that originate from differentiated anterior pituitary cells. ...Thus, this review focuses on the role of the growth hormone/insulin-like growth factor system in pituitary tumorigenesis with particular …
Pituitary adenomas are mostly benign tumours that originate from differentiated anterior pituitary cells. ...Thu …
Human pituitary adenomas show no loss of heterozygosity at the retinoblastoma gene locus.
J Clin Endocrinol Metab. 1994 Apr;78(4):922-7. doi: 10.1210/jcem.78.4.8157722.
J Clin Endocrinol Metab. 1994.
PMID: 8157722
Recently, a high percentage of transgenic mice containing a disrupted RB1 allele have been shown to develop pituitary tumors. To investigate whether RB1 inactivation contributes to the development of human pituitary adenomas, we searched for loss of heterozyg …
Recently, a high percentage of transgenic mice containing a disrupted RB1 allele have been shown to develop pituitary tumors. To inve …
Mutations in adrenocortical tumors.
Horm Metab Res. 1998 Jun-Jul;30(6-7):447-55. doi: 10.1055/s-2007-978913.
Horm Metab Res. 1998.
PMID: 9694578
Review.
These adenomas may have a multicellular origin under the putative action of extra-adrenal and local growth factors. ...Conversely, deletions of the ACTH receptor gene have been recently found in undifferentiated adenomas and in aggressive adrenocortical carci …
These adenomas may have a multicellular origin under the putative action of extra-adrenal and local growth factors. ...Convers …
G-proteins and hormonal signalling in human pituitary tumors: genetic mutations and functional alterations.
Front Neuroendocrinol. 1993 Jul;14(3):214-32. doi: 10.1006/frne.1993.1007.
Front Neuroendocrinol. 1993.
PMID: 8102338
Review.
In the last few years, molecular studies on pituitary adenomas have yielded several lines of evidence supporting a primary pituitary origin for these tumors. ...Mutations constitutively activating GTP-binding proteins have been identified in subsets of …
In the last few years, molecular studies on pituitary adenomas have yielded several lines of evidence supporting a primary …
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